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Caspase-9 Antibody#24050

Caspase-9 Antibody
Caspase-9 Antibody
Caspase-9 Antibody
Caspase-9 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Caspase-9 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Affinity chromatography purified via peptide column

应用ELISA WB ICC

种属反应性Hu

特异性It has no cross response to other members in caspase family.

免疫原类型Peptide

免疫原描述Raised against a peptide corresponding to amino acids 299 to 318 of human caspase-9.

基因/蛋白名称Caspase-9

别名Mch6, Apaf-3, Casp-9

数据库入口号P55211

浓度1mg/ml

配方Supplied in PBS containing 0.02% sodium azide.

保存Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

应用详情
Predicted MW: 46 kd
Western blot analysis of caspase-9 in HeLa whole cell lysate with Caspase-9 antibody at 1:1000 dilution
Immunocytochemistry staining of K562 cells using Caspase-9 antibody at 2 ug/mL.
Immunofluorescence of Caspase-9 in HeLa cells with Caspase-9 antibody at 5 μg/ml.
Immunocytochemistry of Caspase-9 in HeLa cells with Caspase-9 antibody at 5 μg/ml.
背景
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. A novel member in the caspase family was recently identified and designated ICE-LAP6, Mch6, and Apaf-3. Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation. Caspase-9 is also activated by granzyme B and CPP32. Activated caspase-9 cleaves and activates caspase-3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. Caspase-9 play a central role in cell death induced by a wide variety of apoptosis activators including TNFα, TRAIL, anti-CD-95, FADD, and TRADD. Caspase-9 is expressed in a variety of human tissues.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com