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IL-1RAcP Antibody#24067

IL-1RAcP Antibody
IL-1RAcP Antibody
IL-1RAcP Antibody
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产品总价:
产品详情

产品名称IL-1RAcP Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Affinity chromatography purified via peptide column

应用ELISA WB

种属反应性Hu

特异性This polyclonal antibody has no cross activity to other members in the IL-1 receptor family.

免疫原类型Peptide

免疫原描述Raised against a peptide corresponding to amino acids 525 to 540 of human IL-1RAcP, which is identical to those of mouse and rat origins.

基因/蛋白名称IL-1RAcP

别名IL-1RAcP

数据库入口号AF029213

浓度1mg/ml

配方Supplied in PBS containing 0.02% sodium azide.

保存Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

应用详情
Predicted MW: 66 kd
Western blot analysis of IL-1RAcP in HeLa whole cell lysate with IL-1RAcP antibody (C2) at 1:1000 dilution.
Immunofluorescence of IL-1RAcP in HeLa cells with IL-1RAcP antibody at 5 μg/mL.
Immunocystochemistry of IL-1RAcP in HeLa cells with IL-1RAcP antibody at 2 μg/ml.
背景
The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-κB inducing kinae (NIK) and of NF-κB, recruits to the IL-1R complex through IL-1RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com