Tyrosine Hydroxylase Conjugated Antibody - SAB

产品详情

产品名称Tyrosine Hydroxylase Conjugated Antibody

克隆号SD080-02

纯化ProA affinity purified

种属反应性Hu, Ms, Rt

免疫原描述recombinant protein

激发/发射波长AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

别名Dystonia 14 antibody
DYT14 antibody
DYT5b antibody
EC 1.14.16.2 antibody
OTTHUMP00000011225 antibody
OTTHUMP00000011226 antibody
ple antibody
Protein Pale antibody
TH antibody
The antibody
TY3H_HUMAN antibody
TYH antibody
Tyrosine 3 hydroxylase antibody
Tyrosine 3 monooxygenase antibody
Tyrosine 3-hydroxylase antibody
Tyrosine 3-monooxygenase antibody
Tyrosine hydroxylase antibody

数据库入口号Swiss-Prot#:P07101

计算分子量59 kDa

配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

保存Store at -20˚C

应用详情

WB: 1:50,000-1:100,000
IHC: 1:50-1:200
ICC: 1:100-1:500

FC: 1:50-1:100

背景

The enzyme tyrosine hydroxylase (TH), also designated tyrosine 3-monooxygenase (TY3H), catalyzes the conversion of tyrosine to L-dopa, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. TH is thought to play a role in the pathogenesis of Parkinsons disease, which is associated with reduced dopamine levels. Two transcription factor binding sites in the proximal region of the TH gene, the TPA-responsive element (TRE) and the c-AMP responsive element (CRE), have been implicated in the complex regulation of the TH gene. TH is also known to be upregulated by the glia maturation factor (GMF), a Cdc 10/SWI6 motif-containing protein called V-1, and a variety of additional compounds.

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应用

WB免疫印迹
IHC免疫组化
IF免疫荧光
ICC免疫细胞化学
FC流式细胞
IP免疫沉淀
E酶联免疫吸附法
DB免疫斑点法
ChIP染色质免疫沉淀
GICA胶体金免疫层析法
NC阴性对照

种属反应性

Hu人
Ms小鼠
Rt大鼠
Dm果蝇
C线虫
Mk猴
Rb兔
B牛
D狗
P猪
Hm仓鼠
ChHm中国仓鼠
Chk鸡

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ELISA试剂盒

生化试剂盒

重组蛋白

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Tyrosine Hydroxylase Conjugated Antibody#C49178

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