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位置: 首页 > 抗体 > CD8A Rabbit Polyclonal Antibody

CD8A Rabbit Polyclonal Antibody#53289

CD8A Rabbit Polyclonal Antibody
CD8A Rabbit Polyclonal Antibody
CD8A Rabbit Polyclonal Antibody
是否有货: Yes
产品总价:
产品详情

产品名称CD8A Rabbit Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IHC

种属反应性Human,Mouse

免疫原描述Recombinant fusion protein of human CD8A (NP_001759.3).

别名CD8A;CD8;Leu2;MAL;p32

数据库入口号Swiss Prot:P01732
GeneID:925

UniprotP01732

计算分子量21kDa/25kDa/30kDa

实际分子量30kDa

配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Western blot analysis of extracts of mouse pancreas, using CD8A at 1:3000 dilution.
Immunohistochemistry of paraffin-embedded human tonsil using CD8A at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse spleen using CD8A at dilution of 1:100 (40x lens).
背景

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

如果您使用该产品53289发表了文章,请通知我们,让我们可以引用您的文献。

et al,CD155 Cooperates with PD-1/PD-L1 to Promote Proliferation of Esophageal Squamous Cancer Cells via PI3K/Akt and MAPK Signaling Pathways. In Cancers (Basel) on 2022 Nov 15 by Xiyang Tan, Jie Yang, et al..PMID:36428703, , (2022),
PMID: 36428703
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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