免费电话:400-9961-933
邮箱:techcn@signalwayantibody.com
欢迎光临本站
登录 注册 English
位置: 首页 > 抗体 > NR1I3 Rabbit Polyclonal Antibody

NR1I3 Rabbit Polyclonal Antibody#54365

NR1I3 Rabbit Polyclonal Antibody
NR1I3 Rabbit Polyclonal Antibody
NR1I3 Rabbit Polyclonal Antibody
NR1I3 Rabbit Polyclonal Antibody
NR1I3 Rabbit Polyclonal Antibody
是否有货: Yes
产品总价:
产品详情

产品名称NR1I3 Rabbit Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IHC

种属反应性Human,Mouse,Rat

免疫原描述Recombinant protein of human NR1I3.

别名NR1I3;CAR;CAR1;NR1I3

数据库入口号Swiss Prot:Q14994
GeneID:9970

UniprotQ14994

计算分子量30-40kDa

配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunohistochemistry of paraffin-embedded human mammary cancer using NR1I3 at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded human gastric cancer using NR1I3 at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded rat testis using NR1I3 at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using NR1I3 at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded mouse testis using NR1I3 at dilution of 1:200 (40x lens).
背景
This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene.

如果您使用该产品54365发表了文章,请通知我们,让我们可以引用您的文献。

5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

Location :

南京市高新开发区星火路10号人才大厦C座

Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com