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位置: 首页 > 抗体 > DPM1 Rabbit Polyclonal Antibody

DPM1 Rabbit Polyclonal Antibody#55320

DPM1 Rabbit Polyclonal Antibody
DPM1 Rabbit Polyclonal Antibody
是否有货: Yes
产品总价:
产品详情

产品名称DPM1 Rabbit Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IF

种属反应性Human,Mouse,Rat

免疫原描述Recombinant fusion protein of human DPM1 (NP_003850.1).

别名DPM1;CDGIE;MPDS

数据库入口号Swiss Prot:O60762
GeneID:8813

UniprotO60762

计算分子量29kDa

实际分子量30kDa

配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:500 - 1:2000
IF 1:50 - 1:200
Immunofluorescence analysis of U2OS cells using DPM1 at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using DPM1 at 1:1000 dilution.
背景
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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