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位置: 首页 > 磷酸化抗体 > Caldesmon (phospho Ser759) Polyclonal Antibody

Caldesmon (phospho Ser759) Polyclonal Antibody#14027

是否有货: Yes
产品总价:
产品详情

产品名称Caldesmon (phospho Ser759) Polyclonal Antibody

来源种属Rabbit

纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

应用IHC-p,IF(paraffin section),ELISA

种属反应性Human,Mouse,Rat

特异性Phospho-Caldesmon (S759) Polyclonal Antibody detects endogenous levels of Caldesmon protein only when phosphorylated at S759.

免疫原描述The antiserum was produced against synthesized peptide derived from human Caldesmon around the phosphorylation site of Ser759. AA range:725-774

别名CALD1; CAD; CDM; Caldesmon; CDM

数据库入口号Swiss Prot:Q05682
GeneID:800

浓度1 mg/ml

配方Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

保存-20˚C/1

应用详情

Immunohistochemistry: 1/100 - 1/300.
ELISA: 1/10000. Not yet tested in other applications.
背景
caldesmon 1(CALD1) Homo sapiens This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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