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位置: 首页 > 磷酸化抗体 > DEPDC5 (Phospho-Ser993) Antibody

DEPDC5 (Phospho-Ser993) Antibody#SAB640

是否有货: Yes
产品总价:
产品详情

产品名称DEPDC5 (Phospho-Ser993) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化The antibody was purified from rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

应用WB

种属反应性HM

特异性DEPDC5(Phospho-Ser993) Antibody detects endogenous levels of DEPDC5 only when phosphorylated at Ser993.

免疫原描述A synthesized peptide derived from human DEPDC5 around the phosphorylation site of Ser993.

别名GATOR complex protein DEPDC5; DEP domain-containing protein 5; KIAA0645

UniprotO75140

Gene ID9681

实际分子量180kDa

浓度1 mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl,0.02% sodium azide and 50% glycerol.

保存Store at --20˚C/1 year

应用详情
Western Blot: 1/500 - 1/2000
背景
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com