产品描述
Research Area:Cancer
SMILES:CS(=O)(=O)CCNCC1=CC=C(O1)C1=CC2=C(C=C1)N=CN=C2NC1=CC(Cl)=C(OCC2=CC(F)=CC=C2)C=C1
Pathways:Angiogenesis; MAPK; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Receptor:EGFR; HER2/ErbB2; HER2/ErbB2; C-Raf-1; c-Src
Boling pt:750.737C
Melting pt:
Solubility:DMSO: 100 mg/mL (172.09 mM)
Appearance:Faint Yellow Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Rusnak DW, et al. Mol Y Ther, 2001, 1(2), 85-94.