产品详情
产品名称Bendamustine hydrochloride
简述Inhibitors
纯化99.91%
生物活性Bendamustine hydrochloride is an alkylating agent associated with DNA damage with IC50 of 50 μM
基因/蛋白名称DNA/RNA Synthesis inhibitor
CAS号3543-75-7
计算分子量394.72
配方C16H21Cl2N3O2HCl
保存3 years -20˚C powder;2 years -80˚C in solvent;
产品描述
Research Area:Cancer
SMILES:Cl.CN1C(CCCC(O)=O)=NC2=C1C=CC(=C2)N(CCCl)CCCl
Pathways:DNA Damage/DNA Repair
Receptor:DNA synthesis
Boling pt:
Melting pt:149-151C
Solubility:Ethanol: 17 mg/mL (43.06 mM); Water: 2 mg/mL (5.06 mM); DMSO: 78 mg/mL (197.6 mM)
Appearance:White Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Leoni LM, et al. Clin Y Res. 2008, 14(1), 309-317.