产品详情
产品名称Methazolamide
简述Inhibitors
纯化99.00%
生物活性Methazolamide is a carbonic anhydrase inhibitor used to treat glaucoma. Target: Carbonic Anhydrase Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA Ⅱ and bCA IV isoforms, respectively.
基因/蛋白名称Carbonic Anhydrase inhibitor
CAS号554-57-4
计算分子量236.27
配方C5H8N4O3S2
保存3 years -20˚C powder;2 years -80˚C in solvent;
产品描述
Research Area:Other
SMILES:CN1N=C(SC1=NC(C)=O)S(N)(=O)=O
Pathways:Metabolism
Receptor:bCAIV; hCAI; hCAII
Boling pt:402C
Melting pt:208C
Solubility:Ethanol: 3 mg/mL (12.69 mM); DMSO: 47 mg/mL (198.92 mM)
Appearance:White Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Casini A, et al. Bioorg Med Chem Lett, 2003, 13(5), 841-845.
The lead time is currently 7-30 days.
