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位置: 首页 > 抑制剂 > Mirtazapine

Mirtazapine#S0137

是否有货: The lead time is currently 7-30 days.
产品总价:询价
产品详情

产品名称Mirtazapine

简述Inhibitors

纯化99.71%

生物活性Mirtazapine is an antidepressant introduced by Organon International in 1996 used for the treatment of moderate to severe depression. Mirtazapine has a tetracyclic chemical structure and is classified as a noradrenergic and specific serotonergic antidepressant (NaSSA). It is the only tetracyclic antidepressant that has been approved by the Food and Drug Administration to treat depression.

基因/蛋白名称5-HT Receptor antagonist; Adrenergic Receptor antagonist; Dopamine Receptor antagonist; Opioid Receptor agonist

CAS号85650-52-8

计算分子量265.35

配方C17H19N3

保存3 years -20˚C powder;2 years -80˚C in solvent;

产品描述
Research Area:Nervous system
SMILES:CN1CCN2C(C1)C1=CC=CC=C1CC1=C2N=CC=C1
Pathways:Endocrinology/Hormones; Neuroscience; GPCR/G Protein
Receptor:5-HT; HT; Sert (Sodium-dependent); Adrenergic Receptor; DA transporter; Dopamine; κ-opioid receptor
Boling pt:432.4C
Melting pt:114-116C
Solubility:Ethanol: 53 mg/mL (199.73 mM); DMSO: 53 mg/mL (199.73 mM)
Appearance:White Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Laakmann G, et al. Psychoneuroendocrinology. 1999 Oct; 24(7):769-84.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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