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位置: 首页 > 抑制剂 > Quinine

Quinine#S0690

是否有货: The lead time is currently 7-30 days.
产品总价:询价
产品详情

产品名称Quinine

简述Inhibitors

纯化91.75%

生物活性An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

基因/蛋白名称Others; Platelet aggregation; Potassium Channel inhibitor

CAS号130-95-0

计算分子量324.42

配方C20H24N2O2

保存3 years -20˚C powder;2 years -80˚C in solvent;

产品描述
Research Area:Immunology
SMILES:COC1=CC2=C(C=CN=C2C=C1)[C@H]([C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)O
Pathways:Membrane transporter/Ion channel; Others
Receptor:Fe(II)-protoporphyrin IX; Platelet glycoprotein IX; Potassium Channel
Boling pt:495.9C
Melting pt:176-177C
Solubility:Soluble in Water
Appearance:White Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Alumasa JN, et al. J Inorg Biochem. 2010 Sep 21.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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