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位置: 首页 > 抑制剂 > Y-27632 dihydrochloride

Y-27632 dihydrochloride#S1725

是否有货: The lead time is currently 7-30 days.
产品总价:询价
产品详情

产品名称Y-27632 dihydrochloride

简述Inhibitors

纯化99.97%

生物活性Y-27632 2hydrochloride is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.

基因/蛋白名称ROCK inhibitor

CAS号129830-38-2

计算分子量320.26

配方C14H21N3O2HCl

保存3 years -20˚C powder;2 years -80˚C in solvent;

产品描述
Research Area:Other
SMILES:C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
Pathways:Cell Cycle/Checkpoint; Stem Cells
Receptor:ROCK1 (p160ROCK); ROCK2
Boling pt:
Melting pt:
Solubility:Water: 14 mg/mL (43.71 mM); DMSO: 64 mg/mL warmed (199.83 mM)
Appearance:White Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Uehata M, et al. Nature, 1997, 389(6654), 990-994.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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