产品名称Jervine

简述Inhibitors

纯化99.00%

生物活性Jervine's biological activity is mediated via its interaction with the 7 pass trans membrane protein smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the hedgehog signaling pathways. With smoothened inhibited, the GLI1 transcription cannot be activated and hedgehog target genes cannot be transcribed.

基因/蛋白名称Hedgehog/Smoothened inhibitor

CAS号469-59-0

计算分子量425.61

配方C27H39NO3

保存3 years -20˚C powder;2 years -80˚C in solvent;