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位置: 首页 > 抑制剂 > XMD16-5

XMD16-5#S3710

是否有货: The lead time is currently 7-30 days.
产品总价:询价
产品详情

产品名称XMD16-5

简述Inhibitors

纯化99.00%

生物活性XMD16-5 is a tyrosine kinase nonreceptor 2(TNK2) inhibitor. TNK2 mutations have been found in renal Y cells and also in lung, ovarian and gastric Ys. TNK2 genomic amplification has been associated with late stage or metastatic lung and prostate Ys. Overexpression of TNK2 promoted metastasis in a mouse model of breast Y. TNK2 signaling is disrupted in prostate, breast and gastrointestinal tumors.

基因/蛋白名称PPAR inhibitor

CAS号1345098-78-3

计算分子量416.19

配方C23H24N6O2

保存3 years -20˚C powder;2 years -80˚C in solvent;

产品描述
Research Area:Cancer
SMILES:OC(CC1)CCN1C(C=C2)=CC=C2NC3=NC=C4C(N(C)C(C=CC=C5)=C5C(N4)=O)=N3
Pathways:Metabolism
Receptor:TNK2; TNK2
Boling pt:
Melting pt:
Solubility:DMSO: 83 mg/mL (199.28 mM)
Appearance:
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Maxson JE, et al. Y Res. 2016, 76(1):127-38.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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