产品详情
产品名称Jujuboside A
简述Inhibitors
纯化95.00%
生物活性Jujuboside A has neurophysiological inhibitory effects, are more persistent than their Glu inhibitory effects.
Jujuboside A performs its specific sedative and hypnotic effect through not only adjusting GABA receptors subunit mRNAs expression, but also down-regulating the secretion of relevant inflammation cytokines on the intestinal mucosal system to affect the intercellular cytokine network between nerve cells in the brain; may serve as a potential therapeutic agent for the treatment of Alzheimer?s disease.
基因/蛋白名称transporter inhibitor
CAS号55466-04-1
计算分子量1207.36
配方C58H94O26
保存3 years -20˚C powder;2 years -80˚C in solvent;
产品描述
Research Area:Others
SMILES:C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@H](CO[C@H]2O[C@H]3CC[C@@]4([C@H]5CC[C@@H]6[C@H]7[C@@](C[C@@H](O[C@@]78C[C@]6([C@@]5(CC[C@H]4C3(C)C)C)CO8)C=C(C)C)(C)O)C)O)O[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O)O)O[C@H]1[C@@H]([C@H]([C@@H](CO1)O)O)O)O)O)O
Pathways:Metabolism
Receptor:GLU
Boling pt:
Melting pt:
Solubility:Soluble in Pyridine, Methanol, Ethanol
Appearance:
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Liu Z,et al. Jujuboside A, a neuroprotective agent from semen Ziziphi Spinosae ameliorates behavioral disorders of the dementia mouse model induced by Aβ 1-42. Eur J Pharmacol. 2014 Sep 5;738:206-13.
The lead time is currently 7-30 days.
