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位置: 首页 > 抑制剂 > JK-P3

JK-P3#S4425

是否有货: The lead time is currently 7-30 days.
产品总价:询价
产品详情

产品名称JK-P3

简述Inhibitors

纯化98.00%

生物活性JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50 = 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation

基因/蛋白名称VEGFR inhibitor

CAS号942655-44-9

计算分子量323.35

配方C18H17N3O3

保存3 years -20˚C powder;2 years -80˚C in solvent;

产品描述
Research Area:Others
SMILES:COC1=C(C=C(C=C1)C(=O)NC2=NNC(=C2)C3=CC=CC=C3)OC
Pathways:Angiogenesis; Tyrosine Kinase/Adaptors
Receptor:VEGFR2
Boling pt:
Melting pt:
Solubility:DMSO: soluble5mg/mL (clear solution)
Appearance:
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Antony M. Latham, et al. Identification of Receptor Tyrosine Kinase Inhibitors Using Cell Surface Biotinylation and Affinity Isolation. VEGF Signaling pp 121-131 | Cite as

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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