产品名称PF-477736
简述Inhibitors
纯化98.34%
生物活性PF-477736 is a selective, potent and ATP-competitive Chk1 inhibitor with Ki of 0.49 nM and also inhibits VEGFR2, Aurora-A, FGFR3, Flt3, Fms (CSF1R), Ret and Yes. It shows ~100-fold selectivity for Chk1 than Chk2. Phase 1.
基因/蛋白名称c-Fms inhibitor; Chk inhibitor; Src inhibitor; VEGFR inhibitor
CAS号952021-60-2
计算分子量419.48
配方C22H25N7O2
保存3 years -20˚C powder;2 years -80˚C in solvent;