产品名称XL413-hydrochloride

简述Inhibitors

纯化99.00%

生物活性XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. CDC7 kinase inhibitor BMS-863233 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA replication and mitosis, the induction of tumor cell apoptosis, and the inhibition of tumor cell proliferation in CDC7-overexpressing tumor cells. CDC7, a serine-threonine kinase overexpressed in a variety of tumor cell types, plays an essential role in the initiation of DNA replication by activating origins of replication.

基因/蛋白名称Casein Kinase inhibitor; CDK inhibitor; Pim inhibitor

CAS号1169562-71-3

计算分子量326.18

配方C14H13Cl2N3O2

保存3 years -20˚C powder;2 years -80˚C in solvent;