产品详情
产品名称Tubercidin
简述Inhibitors
纯化98.00%
生物活性Tubercidin, an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhibits antifungal and antiviral activities.
基因/蛋白名称DNA/RNA Synthesis inhibitor
CAS号69-33-0
计算分子量266.25
配方C11H14N4O4
保存3 years -20˚C powder;2 years -80˚C in solvent;
产品描述
Research Area:Others
SMILES:NC1=NC=NC2=C1C=CN2[C@@H]1O[C@H](CO)[C@H](O)C1O |r,c:3,5,8,t:1|
Pathways:DNA Damage/DNA Repair
Receptor:DNA/RNA Synthesis
Boling pt:
Melting pt:
Solubility:Ethanol<1 mg/mLDMSO: 53 mg/mL (199.06 mM)Water: <1 mg/mL
Appearance:
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. el Kouni MH., et al. Prevention of tubercidin host toxicity by nitrobenzylthioinosine 5'-monophosphate for the treatment of schistosomiasis. Antimicrob Agents Chemother. 1989 Jun;33(6):824-7.