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位置: 首页 > 重组兔单抗 > INPP4B Rabbit mAb

INPP4B Rabbit mAb#52369

评价
Recombinant
INPP4B Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称INPP4B Rabbit mAb

克隆号S08-7C7

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IHC FC

种属反应性Human,Mouse,Rat

免疫原描述A synthesized peptide derived from human INPP4B

标记Unconjugated

修饰Unmodification

别名4-bisphosphate 4-phosphatase; Inositol polyphosphate 4 phosphatase type II 105kDa; Inositol polyphosphate 4-phosphatase type II; Inpp4b; MGC132014; Type II inositol 3,4 bisphosphate 4 phosphatase; Type II inositol-3;

数据库入口号Swiss-Prot:O15327
GeneID:8821

UniprotO15327

Gene ID8821

计算分子量Calculated MW: 105 kDa; Observed MW: 105 kDa

配方Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

保存Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

应用详情

WB 1:1000-1:2000
IHC 1:100-1:200
FC 1:20-1:100

Western blot detection of INPP4B in Rat Brain,C6 cell lysates using INPP4B Rabbit mAb(1:1000 diluted).Predicted band size:105kDa.Observed band size:105kDa.
背景
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-trisphosphate. Plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles.The lipid phosphatase activity is critical for tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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