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位置: 首页 > 重组兔单抗 > Legumain Rabbit mAb

Legumain Rabbit mAb#52395

评价
Recombinant
Legumain Rabbit mAb
Legumain Rabbit mAb
Legumain Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称Legumain Rabbit mAb

克隆号S06-7G1

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB

种属反应性Human,Mouse,Rat

免疫原描述A synthesized peptide derived from human Legumain

标记Unconjugated

修饰Unmodification

别名AEP; LGMN1; PRSC1

数据库入口号Swiss-Prot:Q99538
GeneID:5641

UniprotQ99538

Gene ID5641

计算分子量Calculated MW: 49 kDa; Observed MW: 57,49,36 kDa

配方Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

保存Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

应用详情

WB 1:1000-1:2000

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Western blot analysis of Legumain expression in HeLa cell lysate.
背景

Swiss-Prot Acc.Q99538.Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation . May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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