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位置: 首页 > 重组兔单抗 > Phospho-Smad2 (Ser250) Rabbit mAb

Phospho-Smad2 (Ser250) Rabbit mAb#52703

评价
Recombinant
Phospho-Smad2 (Ser250) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称Phospho-Smad2 (Ser250) Rabbit mAb

来源种属Recombinant Rabbit

克隆性Monoclonal antibody

克隆号S02-0D1

亚型IgG

纯化Affinity Purified

应用WB

种属反应性Human,Mouse,Rat

免疫原描述A synthetic phosphopeptide corresponding to residues surrounding Ser250 of human Smad2

标记Unconjugated

修饰Phosphorylated

别名JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2

数据库入口号Swiss-Prot:Q15796
GeneID:4087

UniprotQ15796

Gene ID4087

计算分子量Calculated MW:52,48 kDa,Observed MW:58,62 kDa

配方50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

保存Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

应用详情
WB: 1/1000
Western blot detection of Smad2 (phospho-Ser250) in Hela,CHO-K1,C6 using Smad2 (phospho-Ser250) Rabbit mAb(1:1000 diluted)
背景
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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025-58868422

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