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位置: 首页 > 重组兔单抗 > APC Rabbit mAb

APC Rabbit mAb#52713

评价
Recombinant
APC Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称APC Rabbit mAb

来源种属Recombinant Rabbit

克隆性Monoclonal antibody

克隆号S06-2E4

亚型IgG

纯化Affinity Purified

应用WB

种属反应性Human,Rat

免疫原描述A synthetic peptide of human APC

标记Unconjugated

修饰Unmodification

别名GS; DP2; DP3; BTPS2; DESMD; DP2.5; PPP1R46

数据库入口号Swiss-Prot:P25054
GeneID:324

UniprotP25054

Gene ID324

计算分子量Calculated MW:312 kDa,Observed MW:160 kDa

配方50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

保存Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

应用详情
WB: 1/1000
Western blot detection of APC in Hela,A549,HL-60,U2OS cell lysates using APC Rabbit mAb(1:1000 diluted).Predicted band size:312kDa.Observed band size:160kDa.
背景
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Mutations in the APC gene have been found to occur in most colorectal cancers. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Dec 2019]

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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