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位置: 首页 > 重组兔单抗 > FKBP6 Rabbit mAb

FKBP6 Rabbit mAb#52760

评价
Recombinant
FKBP6 Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称FKBP6 Rabbit mAb

来源种属Recombinant Rabbit

克隆性Monoclonal antibody

克隆号S05-4G2

亚型IgG

纯化Affinity Purified

应用WB

种属反应性Human,Mouse,Rat

免疫原描述A synthetic peptide of human FKBP6

标记Unconjugated

修饰Unmodification

别名FKBP36

数据库入口号Swiss-Prot:O75344
GeneID:8468

UniprotO75344

Gene ID8468

计算分子量Calculated MW:37 kDa,Observed MW:37 kDa

配方50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

保存Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

应用详情
WB: 1/2000-1/10000
Western blot detection of FKBP6 in Hela,A549,HL-60,U251,U87-MG cell lysates using FKBP6 Rabbit mAb(1:1000 diluted).Predicted band size:37kDa.Observed band size:37kDa.
背景
Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes (By similarity).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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