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位置: 首页 > 重组兔单抗 > GRSF1 Rabbit mAb

GRSF1 Rabbit mAb#52767

评价
Recombinant
GRSF1 Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称GRSF1 Rabbit mAb

来源种属Recombinant Rabbit

克隆性Monoclonal antibody

克隆号S06-2B5

亚型IgG

纯化Affinity Purified

应用WB

种属反应性Human

免疫原描述A synthetic peptide of human GRSF1

标记Unconjugated

修饰Unmodification

别名G-rich sequence factor 1

数据库入口号Swiss-Prot:Q12849
GeneID:2926

UniprotQ12849

Gene ID2926

计算分子量Calculated MW:53 kDa,Observed MW:53 kDa

配方50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

保存Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

应用详情
WB: 1/1000
Western blot detection of GRSF1 in Hela,Ramos cell lysates using GRSF1 Rabbit mAb(1:1000 diluted).Predicted band size:53kDa.Observed band size:53kDa.
背景
Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. Binds RNAs containing the 14 base G-rich element. Preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-ND5, each of which contains multiple consensus binding sequences (PubMed:23473033, PubMed:23473034, PubMed:29967381). Involved in the degradosome-mediated decay of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules (PubMed:29967381). Acts by unwinding G-quadruplex RNA structures in MT-ncRNA, thus facilitating their degradation by the degradosome (PubMed:29967381). G-quadruplexes (G4) are non-canonical 4 stranded structures formed by transcripts from the light strand of mtDNA (PubMed:29967381).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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