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位置: 首页 > 重组兔单抗 > HIF1 beta Rabbit mAb

HIF1 beta Rabbit mAb#52771

评价
Recombinant
HIF1 beta Rabbit mAb
HIF1 beta Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称HIF1 beta Rabbit mAb

来源种属Recombinant Rabbit

克隆性Monoclonal antibody

克隆号S05-3B2

亚型IgG

纯化Affinity Purified

应用WB IHC

种属反应性Human,Mouse,Rat

免疫原描述Recombinant protein of human HIF1 beta

标记Unconjugated

修饰Unmodification

别名HIF1B; TANGO; bHLHe2; HIF1BETA; HIF-1beta; HIF1-beta; HIF-1-beta

数据库入口号Swiss-Prot:P27540
GeneID:405

UniprotP27540

Gene ID405

计算分子量Calculated MW:87 kDa,Observed MW:87 kDa

配方50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

保存Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

应用详情
WB: 1/1000 IHC: 1/50
Western blot detection of HIF1 beta in Hela,CHO-K1,C6,Ramos using HIF1 beta Rabbit mAb(1:1000 diluted)
Immunohistochemistry of HIF1 beta in paraffin-embedded Human lung cancer tissue using HIF1 beta Rabbit mAb at dilution 1/50
背景
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28396409).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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