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位置: 首页 > 重组兔单抗 > HMGB2 Rabbit mAb

HMGB2 Rabbit mAb#52776

评价
Recombinant
HMGB2 Rabbit mAb
HMGB2 Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称HMGB2 Rabbit mAb

来源种属Recombinant Rabbit

克隆性Monoclonal antibody

克隆号S02-5I5

亚型IgG

纯化Affinity Purified

应用WB IHC

种属反应性Human,Mouse,Rat

免疫原描述A synthetic peptide of human HMGB2

标记Unconjugated

修饰Unmodification

别名HMG 2; HMG B2; HMG-2; HMG2; HMGB2;

数据库入口号Swiss-Prot:P26583
GeneID:3148

UniprotP26583

Gene ID3148

计算分子量Calculated MW:24 kDa,Observed MW:24 kDa

配方50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

保存Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

应用详情
WB: 1/2000-1/10000 IHC: 1/50
Western blot detection of HMGB2 in CHO-K1,Ramos cell lysates using HMGB2 Rabbit mAb(1:1000 diluted).Predicted band size:24kDa.Observed band size:24kDa.
Immunohistochemistry of HMGB2 in paraffin-embedded Human tonsil using HMGB2 Rabbit mAb at dilution 1/50
背景
Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes. Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor binding and/or bringing distant regulatory sequences into close proximity (PubMed:7797075, PubMed:11909973, PubMed:19522541, PubMed:18413230, PubMed:19965638, PubMed:20123072).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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