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位置: 首页 > 重组兔单抗 > Optineurin Rabbit mAb

Optineurin Rabbit mAb#52829

评价
Recombinant
Optineurin Rabbit mAb
Optineurin Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称Optineurin Rabbit mAb

来源种属Recombinant Rabbit

克隆性Monoclonal antibody

克隆号S01-2C5

亚型IgG

纯化Affinity Purified

应用WB IHC

种属反应性Human

免疫原描述Recombinant protein of human Optineurin

标记Unconjugated

修饰Unmodification

别名NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP

数据库入口号Swiss-Prot:Q96CV9
GeneID:10133

UniprotQ96CV9

Gene ID10133

计算分子量Calculated MW:66 kDa,Observed MW:75 kDa

配方50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

保存Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

应用详情
WB: 1/1000 IHC: 1/50
Western blot detection of Optineurin in Hela,A549,HL-60,U2OS,U87-MG cell lysates using Optineurin Rabbit mAb(1:1000 diluted).Predicted band size:66kDa.Observed band size:75kDa.
Immunohistochemistry of Optineurin in paraffin-embedded Human Cholangiocarcinoma using Optineurin Rabbit mAb at dilution 1/50
背景
Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8 (PubMed:27534431). Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation (PubMed:27534431). Plays a role in the activation of innate immune response during viral infection. Mechanistically, recruits TBK1 at the Golgi apparatus, promoting its trans-phosphorylation after RLR or TLR3 stimulation (PubMed:27538435).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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