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位置: 首页 > 重组兔单抗 > CREB Regulated Transcription Coactivator 2 Rabbit mAb

CREB Regulated Transcription Coactivator 2 Rabbit mAb#52873

评价
Recombinant
CREB Regulated Transcription Coactivator 2 Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称CREB Regulated Transcription Coactivator 2 Rabbit mAb

来源种属Recombinant Rabbit

克隆性Monoclonal antibody

克隆号S05-7H2

亚型IgG

纯化Affinity Purified

应用WB

种属反应性Human,Mouse,Rat

免疫原描述Recombinant protein of human TORC2

标记Unconjugated

修饰Unmodification

别名TORC2; TORC-2

数据库入口号Swiss-Prot:Q53ET0
GeneID:200186

UniprotQ53ET0

Gene ID200186

计算分子量Calculated MW:73 kDa,Observed MW:80 kDa

配方50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

保存Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.

应用详情
WB: 1/1000
Western blot detection of TORC2 in Hela,A549,HL-60,U251 cell lysates using TORC2 Rabbit mAb(1:1000 diluted).Predicted band size:73kDa.Observed band size:80kDa.
背景
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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