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位置: 首页 > 单克隆抗体 > PP2A alpha (Phospho-Tyr307) Rabbit mAb

PP2A alpha (Phospho-Tyr307) Rabbit mAb#14129

PP2A alpha (Phospho-Tyr307) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称PP2A alpha (Phospho-Tyr307) Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IHC ICC/IF IP

种属反应性Human Mouse Rat

特异性Phospho-PP2A alpha (Y307) Antibody detects endogenous levels of total Phospho-PP2A alpha (Y307)

免疫原描述A synthesized peptide derived from human Phospho-PP2A alpha (Y307)

别名eplication protein C; PP2A-alpha; Replication protein C; RP-C; PPP2CA; MGC786

数据库入口号Uniprot:P67775

UniprotP67775

计算分子量35kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:500~1:2000
IHC:1:50~1:200
ICC/IF:1:50~1:200
IP:1:50
Western blot analysis of Phospho-PP2A alpha (Y307) in (1) Rat kidney lysate; (2) A431 cell lysate treated with EGF.
产品描述
PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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