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位置: 首页 > 单克隆抗体 > Smad3 (Phospho-Ser423/Ser425) Rabbit mAb

Smad3 (Phospho-Ser423/Ser425) Rabbit mAb#14138

Smad3 (Phospho-Ser423/Ser425) Rabbit mAb
Smad3 (Phospho-Ser423/Ser425) Rabbit mAb
Smad3 (Phospho-Ser423/Ser425) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称Smad3 (Phospho-Ser423/Ser425) Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IHC ICC/IF

种属反应性Human Mouse

特异性Phospho-Smad3 (S423 + S425) Antibody detects endogenous levels of total Phospho-Smad3 (S423 + S425)

免疫原描述A synthesized peptide derived from human Phospho-Smad3 (S423 + S425)

别名JV15-2, MAD-3, MADH3, Mad3, Mothers against DPP homolog 3, Mothers against decapentaplegic homolog 3, SMAD 3, Smad 3

数据库入口号Uniprot:P84022

UniprotP84022

计算分子量55kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:500~1:2000
IHC:1:50~1:200
ICC/IF:1:50~1:200
Western blot analysis of Phospho-Smad3 (S423/S425) expression in A549 cell lysate treated with TGF-?1.
Immunohistochemical analysis of paraffin-embedded human gastric adenocarcinoma, using Phospho-Smad3 (S423 + S425) Antibody.
Immunofluorescent analysis of A549 cells treated with TGF�� , using Phospho-Smad3 (S423 + S425) Antibody.
产品描述
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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