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位置: 首页 > KO/KD抗体 > RSK1(Phospho-Ser380) Rabbit mAb

RSK1(Phospho-Ser380) Rabbit mAb#14173

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RSK1(Phospho-Ser380) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称RSK1(Phospho-Ser380) Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB ICC/IF IP

种属反应性Human Mouse Rat

特异性Phospho-RSK1(S380) Antibody detects endogenous levels of total Phospho-RSK1(S380)

免疫原描述A synthesized peptide derived from human Phospho-RSK1(S380)

别名RSK; HU-1; RSK1; MAPKAPK1A; RPS6KA1;

数据库入口号Uniprot:Q15418

UniprotQ15418

计算分子量90kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情

WB:1:500~1:2000
ICC/IF:1:50~1:200
IP:1:50

Western blot analysis of Phospho-RSK1(S380) expression in A431 cell lysate treated with EGF.
产品描述

Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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