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位置: 首页 > 单克隆抗体 > TrkB (Phospho-Tyr817) Rabbit mAb

TrkB (Phospho-Tyr817) Rabbit mAb#14177

TrkB (Phospho-Tyr817) Rabbit mAb
TrkB (Phospho-Tyr817) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称TrkB (Phospho-Tyr817) Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IHC ICC/IF IP

种属反应性Human Mouse Rat

特异性Phospho-TrkB (Y817) Antibody detects endogenous levels of Phospho-TrkB (Y817)

免疫原描述A synthesized peptide derived from human Phospho-TrkB (Y817)

别名NTRK2; gp145-TrkB; Trk-B; TRKB; Tropomyosin-related kinase B; TrkB tyrosine kinase; Tyrosine kinase receptor B;

数据库入口号Uniprot:Q16620

UniprotQ16620

计算分子量140kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:500~1:1000
IHC:1:50~1:100
ICC/IF:1:50~1:100
IP:1:30
Western blot analysis of Phospho-TrkB (Y817) expression in SH-SY5Y cell lysate treated with BDNF.
Immunohistochemical analysis of paraffin-embedded mouse brain cancer, using Phospho-TrkB (Y817) Antibody.
产品描述
The family of Trk receptor tyrosine kinases consists of TrkA, TrkB and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. TrkA regulates proliferation and is important for development and maturation of the nervous system. Point mutations, deletions and chromosomal rearrangements (chimeras) cause ligand-independent receptor dimerization and activation of TrkA.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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