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位置: 首页 > 单克隆抗体 > PLK1 (Phospho-Thr210) Rabbit mAb

PLK1 (Phospho-Thr210) Rabbit mAb#14206

PLK1 (Phospho-Thr210) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称PLK1 (Phospho-Thr210) Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB

种属反应性Human

特异性Phospho-PLK1 (T210) Antibody detects endogenous levels of Phospho-PLK1 (T210)

免疫原描述A synthesized peptide derived from human PLK1

别名Cell cycle regulated protein kinase; PLK 1; PLK; Polo like kinase 1 ; Serine/threonine protein kinase 13; Serine/threonine protein kinase PLK1; STPK 13;

数据库入口号Uniprot:P53350

UniprotP53350

计算分子量68kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:1000~1:2000
Western blot analysis of Phospho-PLK1 (T210) expression in (1) HeLa cell lysate; (2) HeLa cell treated with nocodazole lysate.
产品描述
Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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