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位置: 首页 > 单克隆抗体 > AKT1 (Phospho-Ser124) Rabbit mAb

AKT1 (Phospho-Ser124) Rabbit mAb#14224

AKT1 (Phospho-Ser124) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称AKT1 (Phospho-Ser124) Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IP

种属反应性Human Mouse Rat

特异性Phospho-AKT1 (S124) Antibody detects endogenous levels of Phospho-AKT1 (S124)

免疫原描述A synthesized peptide derived from human AKT1

别名AKT 1; PKB; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha;

数据库入口号Uniprot:P31749

UniprotP31749

计算分子量60kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:500~1:1000
IP:1:50
Western blot analysis of Phospho-AKT1 (S124) expression in (1) MCF-7 cell treated with Alkaline Phosphatase lysate; (2) MCF-7 cell lysate.
产品描述
Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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