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位置: 首页 > 单克隆抗体 > MLKL (Phospho-Ser358) Rabbit mAb

MLKL (Phospho-Ser358) Rabbit mAb#14251

MLKL (Phospho-Ser358) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称MLKL (Phospho-Ser358) Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IHC

种属反应性Human

特异性Phospho-MLKL (S358) Antibody detects endogenous levels of total Phospho-MLKL (S358)

免疫原描述A synthesized peptide derived from human Phospho-MLKL (S358)

别名hMLKL; Mlkl;

数据库入口号Uniprot:Q8NB16

UniprotQ8NB16

计算分子量54kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:500~1:2000
IHC:1:50~1:200
Western blot analysis of Phospho-MLKL (S358) expression in (1) HT-29 cell lysate; (2) HT-29 cell lysate treated with TNF alpha+ Smac mimetic+ z-VAD.
产品描述
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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