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位置: 首页 > 单克隆抗体 > ERK1/2(Phospho-Thr202/Thr185) Rabbit mAb

ERK1/2(Phospho-Thr202/Thr185) Rabbit mAb#14253

ERK1/2(Phospho-Thr202/Thr185) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称ERK1/2(Phospho-Thr202/Thr185) Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IHC ICC/IF IP

种属反应性Human Mouse Rat

特异性Phospho-ERK1 (T202) + ERK2 (T185) Antibody detects endogenous levels of total Phospho-ERK1 (T202) + ERK2 (T185)

免疫原描述A synthesized peptide derived from human Phospho-ERK1 (T202) + ERK2 (T185)

别名MAPK3; MK03; MNK1; p44-ERK1; P44-ER; ERK-1; ERK1; ERT2; kinase ERK1; MAP kinase 1; MAPK 1;

数据库入口号Uniprot:P27361

UniprotP27361

计算分子量42,44kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:500~1:1000
IHC:1:50~1:200
ICC/IF:1:50~1:200
IP:1:40
Western blot analysis of Phospho-ERK1 (T202) + ERK2 (T185) expression in (1) NIH/3T3 cell lysate; (2) NIH/3T3 cell lysate treated with PDGF.
产品描述
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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