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位置: 首页 > 单克隆抗体 > TAK1(Phospho-Ser439) Rabbit mAb

TAK1(Phospho-Ser439) Rabbit mAb#14266

TAK1(Phospho-Ser439) Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称TAK1(Phospho-Ser439) Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IP

种属反应性Human Mouse Rat

特异性Phospho-TAK1 (S439) Antibody detects endogenous levels of total Phospho-TAK1 (S439)

免疫原描述A synthesized peptide derived from human Phospho-TAK1 (S439)

别名MAP3K 7; MEKK7; Mitogen activated protein kinase kinase kinase 7; TAK1; TGF beta activated kinase 1; TGF1a;

数据库入口号Uniprot:O43318

UniprotO43318

计算分子量72kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:500~1:2000
IP:1:50
Western blot analysis of Phospho-TAK1 (S439) expression in (1) HeLa treated with Calyculin A + IL-1 beta cell lysate; (2) Untreated.
产品描述
Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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