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位置: 首页 > 单克隆抗体 > LRRK2 Rabbit mAb

LRRK2 Rabbit mAb#56018

LRRK2  Rabbit mAb
LRRK2  Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称LRRK2 Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IHC ICC/IF IP

种属反应性Human Mouse Rat

特异性LRRK2 Antibody detects endogenous levels of total LRRK2

免疫原描述A synthesized peptide derived from human LRRK2

别名AURA17; Dardarin antibody;; Leucine rich repeat kinase 2; LRRK 2 antibody; LRRK2; LRRK2_HUMAN; PARK 8; PARK8; RIPK7; ROCO 2; ROCO2;

数据库入口号Uniprot:Q5S007

UniprotQ5S007

计算分子量280kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:500~1:2000
IHC:1:50~1:200
ICC/IF:1:50~1:200
IP:1:50
Western blot analysis of LRRK2 expression in U87-MG cell lysate.
Immunohistochemical analysis of paraffin-embedded human thyroid, using LRRK2 Antibody.
产品描述
Positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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