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位置: 首页 > 单克隆抗体 > KDM1/LSD1 Rabbit mAb

KDM1/LSD1 Rabbit mAb#56086

KDM1/LSD1 Rabbit mAb
KDM1/LSD1 Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称KDM1/LSD1 Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IHC ICC/IF IP

种属反应性Human Mouse Rat

特异性KDM1 / LSD1 Antibody detects endogenous levels of total KDM1 / LSD1

免疫原描述A synthesized peptide derived from human KDM1 / LSD1

别名KDM1;AOF2;BHC110;KIAA0601;LSD1; KDM1A;

数据库入口号Uniprot:O60341

UniprotO60341

计算分子量110kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:1000~1:2000
IHC:1:50~1:200
ICC/IF:1:50~1:200
IP:1:30
Western blot analysis of KDM1/LSD1 expression in Hela cell lysate
Immunohistochemical analysis of paraffin-embedded human colon, using KDM1/LSD1 Antibody.
产品描述
Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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