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位置: 首页 > 单克隆抗体 > PHD2 / prolyl hydroxylase Rabbit mAb

PHD2 / prolyl hydroxylase Rabbit mAb#56226

PHD2 / prolyl hydroxylase Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称PHD2 / prolyl hydroxylase Rabbit mAb

来源种属Rabbit

克隆性Monoclonal

亚型Rabbit IgG

纯化Affinity-chromatography

应用WB IP

种属反应性Human

特异性PHD2 / prolyl hydroxylase Antibody detects endogenous levels of total PHD2 / prolyl hydroxylase

免疫原描述A synthesized peptide derived from human PHD2 / prolyl hydroxylase

别名EGLN1; C1orf12; ECYT3; HIFPH2; HPH2; PHD2; SM-20; SM20; ZMYND6;

数据库入口号Uniprot:Q9GZT9

UniprotQ9GZT9

计算分子量46kDa

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

应用详情
WB:1:500~1:2000
IP:1:50
Western blot analysis of PHD2 / prolyl hydroxylase expression in SH-SY5Y cell lysate.
产品描述
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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