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位置: 首页 > 重组蛋白 > Recombinant Human Interleukin-7

Recombinant Human Interleukin-7#AP60006

Recombinant Human Interleukin-7
是否有货: 3-5days
产品总价:
产品详情

产品名称Recombinant Human Interleukin-7

来源种属Escherichia coli

纯化> 97% by SDS-PAGE and HPLC analyses.

生物活性Fully biologically active when compared to standard. rHuIL-7 stimulates proliferation of PHA-activated human peripheral blood mononuclear cell (PBMC). The specific activity of Recombinant Human IL-7 is > 1.0 x108 Units/mg, which is calibrated against human IL-7 WHO Standard (NIBSC code: 90/530).

内毒素Less than 1 EU/ug of rHuIL-7 as determined by LAL method.

别名LP-1, pre-B cell factor

UniprotP13232

Gene ID3574

计算分子量Approximately 17.4 kDa, a single non-glycosylated polypeptide chain containing 152 amino acids.

配方Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, 150 mM NaCl, pH 7.4.

保存Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- A minimum of 12 months from date of receipt, when stored at ≤ -20 ˚C as supplied.- 1 month, 2 to 8 ˚C under sterile conditions after reconstitution.- 3 months, -20 to -70 ˚C under sterile conditions after reconstitution.

背景
Interleukin-7 (IL-7) is encoded by the IL7 gene and secreted by stromal cells in the red marrow and thymus. It binds to the IL-7 receptor, a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain. IL-7 stimulates the differentiation of hematopoietic stem cells into lymphoid progenitor cells and also stimulates proliferation of B cells, T cells and NK cells. Murine IL-7 has approximately 65% amino acid sequence identity with human IL-7 and both proteins exhibit cross-species activity. IL-7 as an immunotherapy agent has been examined in many human clinical trials for various malignancies and during HIV infection.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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