产品名称Recombinant Human soluble Tumor Necrosis Factor Receptor Type I/TNFRSF1A
来源种属Escherichia coli.
纯化> 97 % by SDS-PAGE and HPLC analyses.
生物活性Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 μg/ml, corresponding to a specific activity of > 2 x104IU/mg in the presence of 0.25 ng/mL of rHuTNF-alpha.
内毒素Less than 0.1 EU/ug of rHusTNF RI/TNFRSF1A as determined by LAL method.
UniprotP19438
Gene ID7132
计算分子量Approximately 21.2 kDa, a single non-glycosylated polypeptide chain containing 190 amino acids.
序列IYPSGVIGLV PHLGDREKRD SVCPQGKYIH PQNNSICCTK CHKGTYLYND CPGPGQDTDC RECESGSFTA SENHLRHCLS CSKCRKEMGQ VEISSCTVDR DTVCGCRKNQ YRHYWSENLF QCFNCSLCLN GTVHLSCQEK QNTVCTCHAG FFLRENECVS CSNCKKSLEC TKLCLPQIEN VKGTEDSGTT
配方Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
保存Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 ˚C as supplied.- 1 month, 2 to 8 ˚C under sterile conditions after reconstitution.- 3 months, -20 to -70 ˚C under sterile conditions after reconstitution.