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位置: 首页 > 重组蛋白 > Recombinant Human Growth Regulated Protein-beta/CXCL2

Recombinant Human Growth Regulated Protein-beta/CXCL2#AP60278

Recombinant Human Growth Regulated Protein-beta/CXCL2
是否有货: 3-5days
产品总价:
产品详情

产品名称Recombinant Human Growth Regulated Protein-beta/CXCL2

来源种属Escherichia coli.

纯化> 97 % by SDS-PAGE and HPLC analyses.

生物活性Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100 ng/ml.

内毒素Less than 1 EU/ug of rHuGRO-尾/CXCL2 as determined by LAL method.

别名MIP2-alpha

UniprotP19875

Gene ID2920

计算分子量Approximately 7.9 kDa, a single non-glycosylated polypeptide chain containing 73 amino acids.

序列APLATELRCQ CLQTLQGIHL KNIQSVKVKS PGPHCAQTEV IATLKNGQKA CLNPASPMVK KIIEKMLKNG KSN

配方Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 50 mM NaCl.

保存Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - A minimum of 12 months from date of receipt, when stored at ≤-20 ˚C as supplied. - 1 month, 2 to 8 ˚C under sterile conditions after reconstitution. - 3 months, -20 to -70 ˚C under sterile conditions after reconstitution.

背景
CXCL2, also named GRO-尾, is belonging to the CXC chemokine family. It is encoded by the gene CXCL2 in humans. CXCL2/GRO-尾 shares 90 % amino acid sequence with CXCL1/GRO-α. All three human GROs (GRO-α, GRO-尾, GRO-纬) are members of the intercrine alpha (chemokine C-X-C) subfamily of chemokine. This chemokine is secreted by monocytes and macrophages. The functional receptor for CXCL2 has been identified as CXCR2. CXCL2 is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. Similar to other GRO proteins, CXCL2 is potent neutrophil attractants and activators. In addition, it is also active toward basophils.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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