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位置: 首页 > 重组蛋白 > Recombinant Human Insulin-like growth factor-binding protein 3 protein(IGFBP3)

Recombinant Human Insulin-like growth factor-binding protein 3 protein(IGFBP3)#AP73424

是否有货: 15-30工作日
产品总价:
产品详情

产品名称Recombinant Human Insulin-like growth factor-binding protein 3 protein(IGFBP3)

纯化>98% as determined by SDS-PAGE and HPLC.

免疫原描述Expression Region:28-291aa
Sequence Info:Full Length of Mature Protein

基因/蛋白名称IGFBP3, IBP3

数据库入口号Uniprot ID: P17936

UniprotP17936

Gene ID3486;

目标蛋白种属Human

计算分子量28.8 kd

标签信息Untagged

序列GASSGGLGPV VRCEPCDARA LAQCAPPPAV CAELVREPGC GCCLTCALSE GQPCGIYTER CGSGLRCQPS PDEARPLQAL LDGRGLCVNA SAVSRLRAYL LPAPPAPGNA SESEEDRSAG EVESPSVSST HRVSDPKFHP LHSKIIIIKK GHAKDSQRYK VDYESQSTDT QNFSSESKRE TEYGPCRREM EDTLNHLKFL NVLSPRGVHI PNCDKKGFYK KKQCRPSKGR KRGFCWCVDK YGQPLPGYTT KGKEDVHCYS MQSK

配方20mM Tris-HCl based buffer, pH8.0

保存Store at -20˚C, for extended storage, conserve at -20˚C or -80˚C. Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.

应用详情

Purity: Greater than 90% as determined by SDS-PAGE.

背景

 IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219,IGFBP-3R. {ECO:0000269|PubMed:20353938}.

背景文献

 PubMed ID: 2464130; 1695633; 7508771; 12853948; 12690205; 15489334; 1697583; 1726837; 15340161; 14561895; 14760718; 16335952; 19159218; 19139490; 20353938; 26091039; 16959974
Research Topic:Cancer

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com