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ORAI2 Antibody#24521

ORAI2 Antibody
ORAI2 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称ORAI2 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Affinity chromatography purified via peptide column

应用ELISA WB ICC

种属反应性Hu Ms

免疫原类型Peptide

免疫原描述Raised against a 15 amino acid peptide from near the carboxy terminus of human ORAI2.

基因/蛋白名称ORAI2

别名Transmembrane protein 142B, TMEM142B, Calcium release-activated calcium channel protein 2

数据库入口号Q96SN7

UniprotQ96SN7

浓度1mg/ml

配方Supplied in PBS containing 0.02% sodium azide.

保存Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western blot analysis of ORAI2 in Jurkat cell lysate with ORAI2 antibody at (A) 1, (B) 2 and (C) 4 ug/mL.
Immunocytochemistry of ORAI2 in Jurkat cells with ORAI2 antibody at 5 ug/mL.
背景
Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI3.

如果您使用该产品24521发表了文章,请通知我们,让我们可以引用您的文献。

et al,A Newly Established Cuproptosis-Related Gene Signature for Predicting Prognosis and Immune Infiltration in Uveal MelanomaInInt J Mol SciOn2023 Jul 12byWei Huang?1?2,?Fan Yang et al..PMID:?37511120, , (2023),
PMID: 37511120
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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