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BAP3 Antibody#24648

BAP3 Antibody
BAP3 Antibody
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产品总价:
产品详情

产品名称BAP3 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Affinity chromatography purified via peptide column

应用ELISA WB IHC

种属反应性Hu

特异性BAP3 is known to have two isoforms; this BAP3 antibody will recognize only isoform 2. Lower molecular weight bands may represent cleavage or degradation products.

免疫原类型Peptide

免疫原描述Raised against a 13 amino acid peptide from near the amino terminus of human BAP3.

基因/蛋白名称BAP3

别名BAI1-associated protein 3, BAIAP3

数据库入口号EAW85671

UniprotEAW85671

浓度1mg/ml

配方Supplied in PBS containing 0.02% sodium azide.

保存Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western blot analysis of BAP3 in SK-N-SH cell lysate with BAP3 antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemical staining of human brain tissue using BAP3 antibody at 5 ug/mL.
背景
BAP3 was initially identified through interaction in a yeast two-hybrid system with the brain-specific angiogenesis inhibitor 1, a p53-target gene that encodes a seven-span transmembrane protein member of the secretin receptor family. BAP3 is predominantly expressed in the brain and possess high homology with Munc13 and synaptotagmin, suggesting that BAP3 may play a role in regulating neurotransmitter release. Recent experiments have shown that BAP3 is induced in certain tumors such as desmoplastic small round cell tumor. Ectopic expression of BAP3 in tumor cells dramatically enhances growth in low serum conditions and colony formation in soft agar, suggesting that the regulated exocytotic pathway may play a role in cancer cell proliferation.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com