免费电话:400-9961-933
邮箱:techcn@signalwayantibody.com
欢迎光临本站
登录 注册 English
位置: 首页 > 磷酸化抗体 > PLCg2(phospho-Tyr1217) Antibody

PLCg2(phospho-Tyr1217) Antibody#11524

PLCg2(phospho-Tyr1217) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称PLCg2(phospho-Tyr1217) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用IHC

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of PLC-g2 onlywhen phosphorylated at tyrosine 1217.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of tyrosine 1217 (F-L-Y(p)-D-T) derived from Human PLCg2.

基因/蛋白名称PLCg2

修饰Phospho

别名PLC-IV; PLC-gamma2; Phospholipase C-gamma-2

数据库入口号Swiss-Prot: P16885
NCBI Protein: NP_002652.2

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情
Predicted MW: 150kd
Immunohistochemistry: 1:50~1:100
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PLC-g2(Phospho-Tyr1217) Antibody #11524(left) or the same antibody preincubated with blocking peptide(right).
背景
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

Yue, C. et al. (1998) J. Biol. Chem. 273, 18023-18027.
Yue, C. et al. (2000) J. Biol. Chem. 275, 30220-30225.
Margolis, B. et al. (1989) Cell 57, 1101-1107.

如果您使用该产品11524发表了文章,请通知我们,让我们可以引用您的文献。

5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

Location :

南京市高新开发区星火路10号人才大厦C座

Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com